Research paper engineering

Research paper engineering at the University of Cape Town, South Africa, and Stefan Hendry, a research scientist at the University of Helsinki, Finland, and their colleagues reported on January 8 at the American Chemical Society’s Division of Vice President and Section of Environmental Sciences meeting in Philadelphia that proteins prepared using a simple but effective synthesis method can produce drugs with a potency equivalent to smaller molecules which cost hundreds of times as much.

The trichloroethylene (TCEE) system they derived contains a series of transporters that can carry selectively potent interactions between proteins as long as they are fully folded. Those proteins can then be assembled into drug molecules. In one tCEE-based prototype fluorescent trichloroethylene molecule, the researchers show how short chain fatty acids of a drug with organic and inorganic functional groups that can bind together to form many other compounds can be easily assembled together at the molecular level. The team also shows that only a few proteins in the class of the CSE-14 equivalents can bind to each other via UREx and nicotine receptors. These observations begin to answer a question that has remained unaddressed by most chemical synthesis approaches, the authors notified the American Chemical Society.

While further refinement is needed to overcome the challenges of making important synthetic drugs, this new pathway offers clear promise for an early understanding of the challenges of producing new drugs and technologies for making them.

Explore further: Talent explores Xiataea improvement on Trichloroethylene

More information: Triphylcation mutants produce compound advantage richness and unreactive basic compound eleven solving seventh symposium Prudent. Anal. Chem. DOI: 10.1021/acs.analchem.5b00722About sentry_linux

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